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Transcripts
DR. TARR:
Now, this is what is believed
to underlie the symptoms that we see in many
patients who meet the case definition of
irritable bowel syndrome. This is a study from
a textbook of gastroenterology in which the
response of normal controls was compared to that
in patients with irritable bowel syndrome who had
a balloon put in their rectum.
The balloon was then distended
with water, to increasing volumes: 20
milliliters, 40 milliliters, 60 milliliters.
Thirty milliliters is one ounce. The normals
said they don't feel anything until about three
ounces were put into the balloon, then they
started to appreciate something. And then after
six ounces were put into this balloon that's
inside the rectum 10 or 15 percent of normals
said "ouch."
However, you can see that on
the red curve, patients that meet the case
definition of irritable bowel syndrome reacted to
this balloon sooner as a population.
