Transcripts
DR. LINGWOOD:
Gb3 is also called CD77, and so
part of the pathology may lie in the fact that
verotoxin can act as an immunosuppressant. We
showed this some 10 years ago that verotoxin
oblates human B cell but not T cell function in
vitro. So it's a B cell inhibitor. One of
the characteristics of VT induced HUS as opposed
to other bacterial toxin induced diseases is the
lack of immune protection.
