Transcripts
DR. LINGWOOD:
So what is the basis of this?
Okay, one of the questions then is: Is the
mucosal Gb3 which is present in cattle
protective? Somehow if you bind the toxin in
the mucosal layer, this first layer of the GI
tract, does it prevent getting into the systemic
circulation and causing disease? These are the
questions that hopefully we will soon answer.
Okay. So the human
gastrointestinal tract does not contain the Gb3
mucosal layer. So how does the toxin get into
the circulation. And nobody knows, essentially.
So this then is a risk factor. Maybe there's a
genetic variation in how toxin transits the
mucosal barrier.
