Transcripts
DR. ROCK:
What is the rationale for using
cryosupernatant? Well, the large molecular weight
multimers of von Willebrand factor which are in
plasma have been associated, as I mentioned
earlier, certainly with the chronic relapsing
forms of TTP and more recently Furlan and Tsai
have indicated that they have a role in the
commoner acute presenting form.
We know for sure that
aggregation of platelets in TTP plasma is
enhanced by the use of cryosupernatant rather than
plasma. And von Willebrand factor has been
demonstrated to actually be present in the clot.
