Transcripts
DR. ROCK:
The first study and the report
from Byrnes led us to then carry out another
study. First of all, we took a TTP patient who
had failed the treatment with plasma exchange,
and as you will recall about 20 percent don't
respond, and we carried out plasma exchange with
cryosupernatant. This is a pilot study.
We had to start with a patient
who had failed because on the other side of the
coin we knew for sure that the fresh frozen
plasma was effective in 80 percent of cases. We
had no idea if this would be effective in more
than the few cases reported in the literature.
But because of the success that we
had in our early failed patients, we then went
on to treat untreated patients with cryosupernatant.
Both of these, I must tell you, are pilot
studies for which we are simply looking for an
indication of benefit to do the larger randomized
prospective clinical trials in sufficient numbers
to statistically prove that benefit.
