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DR. ROCK:
These are the plots that show
the relative effectiveness of plasma exchange
versus plasma infusion from time of initiation
of treatment. And you can see that the
difference between exchange in the infusion arms
certainly holds up with time.
Now, particularly in this
audience, I would like to emphasize the effect
of plasma exchange and plasma infusion on
patients who have impaired renal function
because, once again, our group struggled with
this definition of TTP vs. HUS only three
weeks ago when we're trying to get ready to
submit another grant.
At this point in time we feel
it is extremely difficult, except in those very
overt, strong cases, where you've got a known
verotoxin bloody diarrhea associated in an adult
that you can call that truly HUS and not TTP
with renal manifestations.
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