Transcripts
DR. ROCK:
Which is to say that if you go
back into the 1960 literature, 85 percent of all
patients died who had TTP. If you are now
looking at the outcome from these studies, you
will see that in both arms the majority of
patients survived and at six months we had a 78
percent survival with plasma exchange, which is
statistically significant and improved over the
infusion arm.
I should note to you that
patients did crossover to the trial, but during
this crossover, if anything, they prejudiced the
exchange arm in a negative way so that these
results would be considered the worst case
scenario that we would get with plasma exchange.
And in actual fact, if you don't consider the
crossover, the results are likely to have been
better, but statistically, of course, we have to
look at crossovers.
