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DR. MAUSETH:
Now, when you look at sugar
metabolism you have these big cells here and
each of the cells has a place on the surface of
the cell called a receptor. Insulin molecules
float around in the blood stream and attach to
the receptor, and when they're attached to the
receptor, they allow sugars to go into the cells
and to nourish the cells.
When sugar doesn't get into the
cells, the cells essentially go into a state of
starvation and that is where you get weight loss
and muscle breakdown and lethargy and those kinds
of symptoms.
And in general, when the sugar
stays in the blood stream, then it gets into the
kidneys. And when it gets into the kidneys in
the normal kidney, then it will cause the person
to start urinating more than normal. Now, keep
this in mind because we're going to come back to
the difference, here.
There are a lot of things that
can affect how the insulin attaches to the
islet's receptor, here. And there are
many things that can affect the way the receptor
works, and one of those is stress.
Stress will make these receptors
not as active as normal. Stress also can cause
other hormones to create more sugar to come into
the body. Obesity will make the receptors not
work as well. And puberty will also make those
not work as well.
And so when we come -- later on
in the talk, we will be discussing when you
might look for onsets of diabetes. There will
be a difference between type one and type two
diabetes.
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