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DR. LINGWOOD:
      And here, this is an entero hemorrhagic E. coli binding to a phospholipid - phosphatidyl ethanolamine, extracted from the plasma membrane. And the bundle forming pillus will do this, also. This binding subsequently induces apoptosis. So maybe by inducing apoptosis in the epithelial layer, you also increase the permeability, if you like, and allow verotoxin to enter. So the cell binding of an organism may facilitate the transit of the toxin.




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