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DR. LINGWOOD:
And here, this is an entero
hemorrhagic E. coli binding to a phospholipid -
phosphatidyl ethanolamine, extracted from the
plasma membrane. And the bundle forming pillus
will do this, also. This binding subsequently
induces apoptosis. So maybe by inducing
apoptosis in the epithelial layer, you also
increase the permeability, if you like, and allow
verotoxin to enter. So the cell binding of an
organism may facilitate the transit of the toxin.
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