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DR. LINGWOOD:
      It can result in a variety of effects. And it's also reflected, I believe, in this chart which is the -- the outcome of 0157 infections whether -- I'm not going to go through this -- but what I'm saying is I'm sure all of you are aware everyone who has a verotoxin producing 0157:H7 infection does not develop HUS.
      Why is that? What I would like to say is that one of the reasons is the differential expressions of the receptor with relation to the lipid structure of the Gb3 molecules in the relevant tissues.
      And this is the same, this is before, showing that most people recover from VTEC and only a few, five to ten percent, actually go onto develop full blown HUS.




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