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DR. CORNEL:
      We had to make a difficult decision at this stage as to how we would maintain the bypass circuitry. I changed the access from the femoral vessels, which meant a very small incision in the groin, to one directly into the heart, which meant a great big incision through the breast bone.
      We also opened up the sheathes around the muscles in her leg to let the muscles bulge out and get the pressure off them. The muscles underneath actually looked quite viable and we -- we wondered if there wasn't some actual specific process related to the HUS going on with these muscles. It would not be surprising.
      The incision in the chest was a nightmare, as we knew it would be. It just bled and bled and bled and we opened and closed and put stitches and packs and so on. It was awful, but we knew it would be.
      And we had another alternative which was to use the big artery and vein in the neck. But we were so concerned to preserve brain function that we would not use that.




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