Transcripts
DR. BRANDT:
And just a word about study size: if there were one patient who had an abnormality after HUS and you looked at 10 patients, then that's a 10 percent incidence of an abnormality, which seems pretty dramatic.
But if actually a hundred patients came back and there was only that one abnormality, it becomes less impressive. And if a thousand patients follow-up after HUS and there's still just the one abnormality, that's a less impressive outcome again.
So the more people you can follow and the larger the study group, the less one or two patients will influence your results and your conclusions. So small studies have less power to make forceful statements about your conclusions.
