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DR. BRANDT:
      Just to point out the rarity of HUS, the incidence of HUS is about two cases per hundred thousand children per year, roughly.
      By comparison, the most common form of childhood leukemia, acute lymphotic leukemia, is about six times more common.
      Congenital heart disease is about 50 times more common and urinary tract infections about 100 times more common.
      Because HUS is a rare disease, and because of the problems comparing children from different outbreaks, it can be hard to find enough patients to create a study from which to draw reliable conclusions.




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