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DR. ROCK:
      In concluding my talk this morning I would like to remind you that we have quite effective therapies now in TTP/HUS, but it's necessary to start those therapies very early, the minute we hear of the patient with this disorder.
      Nonetheless, it continues to have significant mortality, a death rate of 20 or 10 percent in people who are previously quite healthy, suffer acute insult, and develop a microangiopathy is not acceptable in today's world. We have to work very hard at that to resolve this. I will remind you that relapse occurs in 35 percent of the cases and the occurrence of that relapse interval is variable. So patients have to be involved in self-monitoring and work with their doctor to let them know of changing signs. Thank you.




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