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DR. ROCK:
Nonetheless, we have come a long
way to define what is going on in TTP. And
one thing we know for certain is that this
disorder does present in multiple forms. It
will present as an acute form in which a
previously well 35-year-old woman suddenly comes
down with thrombocytopenia and schistocytic
hemolytic anemia and if not treated, will go on
to develop those other signs in the pentad.
There is a chronic relapsing
form. I will give you a bit of information on
the number of our patients that relapse, shortly,
but there's also a form that appears to be
congenital in which individuals are born with a
particular propensity to have recurrent episodes
of TTP and who can be treated, particularly when
they are young simply by infusing one to two
units of plasma.
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