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DR. ROCK:
      Nonetheless, we have come a long way to define what is going on in TTP. And one thing we know for certain is that this disorder does present in multiple forms. It will present as an acute form in which a previously well 35-year-old woman suddenly comes down with thrombocytopenia and schistocytic hemolytic anemia and if not treated, will go on to develop those other signs in the pentad.
      There is a chronic relapsing form. I will give you a bit of information on the number of our patients that relapse, shortly, but there's also a form that appears to be congenital in which individuals are born with a particular propensity to have recurrent episodes of TTP and who can be treated, particularly when they are young simply by infusing one to two units of plasma.




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