Transcripts
DR. LINGWOOD:
And what some scientists in
Melbourne, Australia did was really clever is
that they transfected these genes into E. coli
and now this E. coli expresses a high density of
Gb3 like structure on its LPS on the surface and
can bind verotoxin.
They showed in an animal model
that oral coinfection of this E. coli with a
verotoxin producing E. coli completely prevented
any VT-induced pathology. So this organism mops
VT in the GI tract and may provide a novel
biotic approach to the prevention of disease.
