Transcripts
DR. LINGWOOD:
CD19 is the primary B cell
differentiation antigen and it exists in all B
cells. And this is the N-terminal extracellular
domain of CD19. And what is shown in pink here
are the amino acid sequences that are related to
verotoxin. This is a big surprise. There are
these regions that are looped out by these
disulfide linkages which bring these regions
close together so that CD19 actually binds Gb3
on the B cell surface.
