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DR. BRANDT:
I looked at studies that only included E. coli associated patients so we're not confusing TTP or strep pneumonia HUS or other types of things; this is the predominant cause of HUS. I looked at studies that on average had at least five years of follow-up.
HUS was first identified in children really as a separate disease in about 1956. And it really wasn't until the `70s that we started to see and to identify E. coli as the cause and started to see some larger outbreaks.
So -- when you think of somebody's life span of 70 years -- there is not an enormous amount of study time to predict what a child who has HUS when they're four years old will be like when they're 60 or 70 years old.
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