Vibrio cholerae

Gram-negative, non-spore forming rod, facultative anerobe.

Incubation Period

From a few hours to 5 days, usually 2-3 days.

Symptoms

Profuse watery diarrhea and vomiting, with leg cramping. The rapid loss of body fluids leads to dehydration and shock without immediate treatment, death can occur within hours.

Illness Duration

3-7 days.

Complications

Can cause life-threatening dehydration.

Infective Dose

High levels of the bacteria are needed to cause illness (10^6 - 10^11 CFU's).

Treatments

Cholera can be treated with oral rehydration solution of sugar and salts to be mixed with clean water and consumed in large amounts. The most severe cases require intravenous fluids. Antibiotics will shorten diminish the severity of the illness, but rehydration is more important.

Testing

Stool culture, with specified growth media.

Communicability

Communicable for the duration of illness to a few days after recovery; a carrier state may exist for several months.

Nationally Notifiable

State public health departments and the CDC are contacted when a case of Cholerae is seen in the United States.

Vibrio parahaemolyticus

A halophilic, facultative anaerobe, gram-negative, rod-shaped bacterium.

Incubation Period

Symptoms usually occur within 24 hours, but can range from 4-96 hours.

Symptoms

Watery diarrhea, abdominal cramps, nausea, vomiting, and possible fever. Wound or blood infections can also occur.

Illness Duration

Usually 2-5 days, typically self-limited.

Complications

Blood or wound infections, and death are uncommon and occur more often in persons with underlying medical conditions, such as alcoholism and liver disease.

Infective Dose

Ingestion of greater than 106 organisms, however the infective dose may be lower depending on antacid use, or health of the individual.

Treatments

Supportive care. Antibiotics recommended for severe cases.

Testing

Cultures of stool, wound, or blood. Special media is needed.

Communicability

Not communicable between persons.

Nationally Notifiable

To improve the CDC's ability to monitor trends, infections caused by V. parahaemolyticus and other Vibrio species became nationally notifiable in 2007.

Vibrio vulnificus

Halophilic, gram-negative, opportunistic pathogen

Incubation Period

1-7 days, death can occur within 24 hours without treatment.

Symptoms

Vomiting, diarrhea, abdominal pain, bacteremia or primary septicemia - fever and chills, decreased blood pressure, known as septic shock. Blistering skin lesions or wound infections. More common in immune compromised individuals, or in persons with liver disease.

Illness Duration

2-8 days.

Complications

Can be fatal in patients with liver disease and the immunocompromised. Septicemia in patients is fatal about 50% of the time.

Infective Dose

The infective dose for gastrointestinal symptoms in healthy individuals is unknown but for predisposed persons, septicemia may occur with fewer than 100 total organisms.

Treatments

Supportive care and antibiotics are recommended. Attention to any wounds should be given with amputation of infected limbs sometimes necessary.

Testing

Stool, wound, or blood cultures, with special media to grow required.

Communicability

Not communicable between persons.

Nationally Notifiable

Infections are notifiable. Thirty-three states now report to state public health officials and the CDC.

Vibrio






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